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Knockdown of STEAP3 inhibits tumor growth in an orthotopic mouse model. (A and B) Representative Images of mouse brains implanted with GBM#01 or GBM#P3 GSCs transduced with sh-Ctrl (n = 5) or sh-STEAP3#1 (n = 5). Representative H&E staining from indicated groups. Scale bar = 2 mm. (C and D) Survival analysis for animals implanted with GBM#01- or GBM#P3-sh-Ctrl or -sh-STEAP3#1 GSCs (P < .05 by the log-rank test).
