Table II.

VAS, Lequesne and WOMAC scores in the Ozone and Control groups at Baseline, at 6 weeks and at 3, 6 and 12 months after treatment.

			WOMAC
Time-point/group	VAS	Lequesne	Pain	Stiffness	Physical function	Total
Baseline
Ozone group	7.52±1.57	15.07±3.82	12.36±2.79	2.95±1.75	55.12±6.99	70.43±8.37
Control group	7.66±1.32	14.26±2.64	13.55±3.45	3.32±2.04	57.45±6.16	73.68±10.07
P-valuea	0.682	0.280	0.091	0.394	0.120	0.119
6 weeks
Ozone group	3.69±1.14	5.86±2.40	4.90±2.25	1.67±1.12	28.55±5.00	35.12±6.23
Control group	4.53±1.67	7.89±2.71	6.97±2.45	2.42±1.31	33.84±6.26	43.24±7.08
P-valuea	0.010	0.001	<0.001	0.008	<0.001	<0.001
P-valueb	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
P-valuec	<0.001	<0.001	<0.001	0.014	<0.001	<0.001
3 months
Ozone group	3.81±1.57	6.02±2.05	5.69±2.32	2.00±1.12	28.98±7.35	36.67±8.11
Control group	4.74±1.54	8.97±2.14	7.71±2.04	2.61±1.33	34.82±7.61	45.29±8.51
P-valuea	0.009	0.046	<0.001	0.034	<0.001	<0.001
P-valueb	<0.001	<0.001	<0.001	0.002	<0.001	<0.001
P-valuec	<0.001	<0.001	<0.001	0.049	<0.001	<0.001
6 months
Ozone group	4.71±1.42	7.19±2.24	5.83±1.81	2.25±1.47	29.95±6.67	38.02±7.66
Control group	5.97±1.23	9.21±2.04	7.95±1.90	2.76±1.56	36.50±8.77	47.00±8.70
P-valuea	<0.001	0.037	<0.001	0.042	<0.001	<0.001
P-valueb	<0.001	<0.001	<0.001	0.021	<0.001	<0.001
P-valuec	<0.001	<0.001	<0.001	0.126	<0.001	<0.001
12 months
Ozone group	5.17±1.43	8.74±2.89	6.71±2.38	2.33±1.37	32.76±6.64	41.19±7.64
Control group	6.76±1.45	10.08±3.03	8.55±2.44	2.68±1.47	37.87±6.96	58.84±7.48
P-valuea	<0.001	0.046	<0.001	0.047	0.001	<0.001
P-valueb	<0.001	<0.001	<0.001	0.032	<0.001	<0.001
P-valuec	0.008	<0.001	<0.001	0.080	<0.001	<0.001

^aOzone vs. control groups at the same time points.

^bOzone vs. baseline ozone group.

^cOzone vs. the baseline control group. Values are expressed as the mean ± standard deviation. WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index; VAS, Visual Analogue Scale.