. 2018 May 17;9(22):5052–5056. doi: 10.1039/c8sc01561a

Table 1. Reaction conditions for the photoredox/enzyme catalysis cascade ^a .


Entry	Biocatalyst	t/h	Yield [e.e.] (%) ^b
1	E. coli (MAO-N-9) whole cell/180 mg	20	92 [91]
2	E. coli (MAO-N-9) whole cell/180 mg	30	92 [>99]
3	—	10	95 [0]
4	E. coli (empty) whole cell/120 mg	20	>95 [0]
5	E. coli (MAO-N-9) lysate/180 mg	20	83 [77]

^aReaction conditions: 1a (10 mM), Na₃[Ir(sppy)₃] (0.1 mM), AscH₂ (200 mM), biocatalyst (180 or 120 mg, wet weight of cell pellets) in 1.0 mL phosphate buffer solution (pH 8.0) at ambient temperature with 405 nm LED (3 W) irradiation on a shaking agitator (at 200 rpm) under air.

^bYields were determined by ¹H NMR analysis, enantiomeric excess was determined by GC on a chiral stationary phase (see ESI for details).

Table 1. Reaction conditions for the photoredox/enzyme catalysis cascade a .

Table 1. Reaction conditions for the photoredox/enzyme catalysis cascade ^a .