TABLE 1:

Gene Ontology cellular compartment analysis of significant genes from RNA sequencing (top 25).

	HyT36			Nigericin			Xyloside
Rank	Term ID	Term	logP	Term ID	Term	logP	Term ID	Term	logP
1	GO:0005794	Golgi apparatus	−7.27	GO:0044424	Intracellular part	−94.92	GO:0005622	Intracellular	−122.98
2	GO:0012505	Endomembrane system	−6.92	GO:0005622	Intracellular	−91.58	GO:0044424	Intracellular part	−119.21
3	GO:0044420	Extracellular matrix part	−6.70	GO:0043229	Intracellular organelle	−65.17	GO:0043229	Intracellular organelle	−87.34
4	GO:0005719	Nuclear euchromatin	−6.69	GO:0043226	Organelle	−59.93	GO:0043226	Organelle	−83.98
5	GO:0005581	Collagen trimer	−6.35	GO:0043231	Intracel. membrane-bd. orgl.	−57.98	GO:0043227	Membrane-bd. orgl.	−78.50
6	GO:0005604	Basement membrane	−6.25	GO:0043227	Membrane-bd. orgl.	−53.23	GO:0043231	Intracel. membrane-bd. orgl.	−78.05
7	GO:0000791	Euchromatin	−6.19	GO:0005737	Cytoplasm	−43.40	GO:0005737	Cytoplasm	−67.65
8	GO:0030127	COPII vesicle coat	−5.72	GO:0044444	Cytoplasmic part	−39.09	GO:0044446	Intracellular organelle part	−40.63
9	GO:0043227	Membrane-bd. orgl.	−5.32	GO:0044446	Intracellular organelle part	−36.24	GO:0044444	Cytoplasmic part	−40.24
10	GO:0032587	Ruffle membrane	−5.31	GO:0044422	Organelle part	−34.27	GO:0044422	Organelle part	−38.25
11	GO:0005578	Proteinaceous ECM	−5.29	GO:0005829	Cytosol	−33.08	GO:0044464	Cell part	−38.00
12	GO:0044424	Intracellular part	−5.25	GO:0044464	Cell part	−28.90	GO:0005623	Cell	−37.80
13	GO:0005783	Endoplasmic reticulum	−5.10	GO:0005623	Cell	−28.78	GO:0005634	Nucleus	−34.62
14	GO:0005622	Intracellular	−4.66	GO:0031981	Nuclear lumen	−22.50	GO:0070013	Intracellular organelle lumen	−23.45
15	GO:0005595	Collagen type XII trimer	−4.62	GO:0005634	Nucleus	−22.14	GO:0044428	Muclear part	−22.75
16	GO:0005585	Collagen type II trimer	−4.62	GO:0070013	Intracellular organelle lumen	−22.01	GO:0043233	Organelle lumen	−21.68
17	GO:0043231	Intracel. membrane-bd. orgl.	−4.44	GO:0031974	Membrane-enclosed lumen	−21.35	GO:0005856	Cytoskeleton	−21.39
18	GO:0043226	Organelle	−4.32	GO:0043233	Organelle lumen	−20.85	GO:0031974	Membrane-enclosed lumen	−21.09
19	GO:0031012	Extracellular matrix	−4.16	GO:0044428	Nuclear part	−18.23	GO:0005912	Adherens junction	−19.99
20	GO:0048770	Pigment granule	−4.15	GO:0043228	Nonmembrane-bd. orgl.	−16.27	GO:0043228	Nonmembrane-bd. orgl.	−19.65
21	GO:0042470	Melanosome	−4.15	GO:0043232	Intracel. nonmbr-bd. orgl.	−16.27	GO:0043232	Intracel. nonmbr-bd. orgl.	−19.65
22	GO:0044431	Golgi apparatus part	−3.93	GO:0005654	Nucleoplasm	−15.29	GO:0012505	Endomembrane system	−18.94
23	GO:0005615	Extracellular space	−3.83	GO:0015630	Microtubule cytoskeleton	−14.40	GO:0031981	Nuclear lumen	−18.92
24	GO:0000139	Golgi membrane	−3.71	GO:0031090	Organelle membrane	−12.73	GO:0005829	Cytosol	−18.55
25	GO:0030662	Coated vesicle membrane	−3.65	GO:0005815	Microtubule organizing center	−12.21	GO:0070161	Anchoring junction	−16.68