Table 4.
Compd | IC50 (μM)a
|
||||
---|---|---|---|---|---|
K562 | Molt-4 | HEL | PC-3 | SK-N-BE(2) | |
9a | NDb | ND | 2.27 | ND | ND |
9d | 1.75 | 1.24 | 0.69 | 1.27 | 0.93 |
9h | 2.83 | 2.46 | 1.15 | 11.35 | 1.92 |
9m | 1.54 | 0.75 | 0.53 | 4.82 | 0.96 |
9n | 1.48 | 0.70 | 0.58 | 3.23 | 1.01 |
23a | 5.28 | 5.13 | 2.75 | 10.19 | 8.98 |
MS-275 | 1.32 | 0.65 | 0.48 | 4.89 | 0.33 |
Assays were performed in replicate (n ≥ 2), the SD values are <20% of the mean.
Not determined.