Table 5.
Data of in vivo study with U937 xenograft model.
Cpd No. | Does (mg/kg) |
Tumor growth inhibition (TGI %) | Relative increment ratio (T/C %) | Mice body weight (g) |
---|---|---|---|---|
11a | 100 | 51 | 49 | 25.04 ± 1.31 |
MS275 | 50 | 60 | 32 | 19.77 ± 0.61 |
Ctrl | / | / | / | 25.39 ± 1.18 |