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Data of in vivo study with HCT116 xenograft model.
| Cpd No. | Does (mg/kg) |
Tumor growth inhibition (TGI %) | Relative increment ratio (T/C %) | Mice body weight (g) |
|---|---|---|---|---|
| 11a | 100 | 49 | 59 | 21.59 ± 1.05 |
| SAHA | 100 | 32 | 73 | 21.23 ± 0.63 |
| MS275 | 50 | 62 | 46 | 18.87 ± 0.80 |
| Ctrl | / | / | / | 19.91 ± 1.26 |
