Table 1.
Alignment of predicted amino acid sequences of S. chinensis MHC class II genes (DQB and DRB)
| * * * | ** | * * | ** * | * ** * | * ** | |||
|---|---|---|---|---|---|---|---|---|
| 1112222222 | 2223333333 | 3334444444 | 4445555555 | 5556666666 | 6667777777 | 7778888888 | 8 | |
| 7890123456 | 7890123456 | 7890123456 | 7890123456 | 7890123456 | 7890123456 | 7890123456 | 7 | |
| Soch-DRB*01 | FSNGTERVRL | LVRDIYNQEE | TLRYDSDVGE | YRAVTELSRQ | EAEKRNSQKD | LLERRRAEVD | TVCRHNYRLG | E |
| Soch-DRB*02 | .........F | VM.RT..R.. | F..F...... | .......G.R | T...W..... | ...QN..... | .Y......VV | . |
| Soch-DQB*01 | ----.....F | VN.N...R.. | YV.F...... | F......G.R | T..YW..... | ....K...L. | .--------- | - |
| Soch-DQB*02 | ----.....H | VS.Y...R.. | FV.F...... | F......G.P | D..YW...E. | ....K..D.. | .--------- | - |
Dots indicate residues identical to the reference sequence Soch-DRB*01. Putative peptide binding sites according to the 3-dimensional structure of human HLA DR1 molecules are marked with asterisks.