Table 3.
Locus | Positions | Codons | d N | d S | ω(dN/dS) | P value |
---|---|---|---|---|---|---|
DQB | All | 57 | 0.037 (0.012) | 0.009 (0.009) | 4.13 | 0.037 |
PBR | 14 | 0.080 (0.028) | 0 (0) | ∞ | 0.003 | |
Non-PBR | 43 | 0.024 (0.013) | 0.012 (0.013) | 2 | 0.26 | |
DRB | All | 71 | 0.073 (0.019) | 0.016 (0.008) | 4.54 | 0.0003 |
PBR | 19 | 0.195 (0.073) | 0.031 (0.023) | 6.29 | 0.009 | |
Non-PBR | 52 | 0.036 (0.015) | 0.011 (0.008) | 3.27 | 0.014 |
d N and dS were computed according to the Nei–Gojobori method, with standard errors obtained through 1000 bootstrap replicates in parentheses; P is the probability that dN and dS are different using a Z-test.