HSP70 expression in RPE. Expression area 7 hours after laser treatment at (A) 25%, (B) 30%, (C) 40%, and (D) 100% energy. Expression area is indicated by dotted lines. In 100%, solid line indicates inner limit of HSP70 expression. (E) Average expression (red) or damage (black) area per 100 spots for 25% (NHSP = 200), 30% (NHSP = 238, Ndamage = 250), 40% (NHSP = 150, Ndamage = 250), 100% (NHSP, Ndamage = 54), and 114% (NHSP = 54) energy. Solid bars show model predictions while striped bars depict experimental measurements. Error bars on experimental measurements give interquartile (25%–75%) range.