Table I.
Criteria | Characteristics |
---|---|
Nasal or oral inflammation | Painful or painless oral ulcers, purulent or bloody nasal discharge |
Abnormal chest radiograph | Nodules, fixed infiltrates, cavities |
Urinary sediment | Microhematuria (>5 red blood cells per high-power field), red cell casts |
Granulomatous inflammation at biopsy | Involvement of the wall of an artery/arteriole, involvement of the perivascular/extra vascular space |
The presence of two or more of the four criteria is associated with a sensitivity of 88.2% and a specificity of 92% for Wegener granulomatosis.