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. 2018 Jun 4;5:116. doi: 10.3389/fvets.2018.00116

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Copyright © 2018 Ilyinskaya, Mukhina, Soboleva, Matveeva and Chumakov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Oncolytic Sendai virus MCT treatments results (Cases 1 and 2). Case 1. Male dog of mixed breed of 7 years old was presented with cutaneous, ulcerated, and poorly differentiated mastocytoma (35 mm diameter) located near his anus. The tumor stage was not assigned. (1) Primary tumor before any treatment; (2) MCT site, 2 weeks after the first virus treatment; (3) MCT site, 4 weeks after the first virus treatment. Case 2. Male German shorthaired pointer of 9 years old was presented with subcutaneous, regional (stage 2) intermediately differentiated mastocytoma. The primary tumor was excised without clean margins (is not shown). (1) MCT secondary growth 1 week after the surgical procedure; (2) MCT site, 2 weeks after the first virus treatment; (3) MCT site, 5 weeks after the first virus treatment.