Figure 5.
Effect of FOXA2 on tumorigenesis of colon cancer cells in nude mice. (A) Representative images of xenograft formed by HCT116 cells transfected with FOXA2 interference sequence (siR-FOXA2). (B) Weight of tumors from nude mice inoculated with HCT116 or HT29 cells that were transfected with siR-FOXA2. *P<0.05 vs. negative control (NC). (C) Expression of E-Cadherin and Vimentin in xenograft tissues derived from HCT116 cells that were transfected with siR-FOXA2. Immunohistochemistry was used to detect the expression of E-Cadherin and Vimentin. Magnification, ×200.