Table 3.

Maternal and infant outcome measures utilized by the pregnancy registry.

Infant outcomes

Maternal outcomes

(1)Major malformations Defined as structural abnormalities with surgical, medical, or cosmetic importance Note: The conditions listed below were excluded as major malformations Minor physical features Deformities that represent the normal response of fetal tissue to mechanical forces, e.g.positional plagiocephaly, Physical features at birth in a preterm infant that are normally present before 37 weeks of gestation Findings on prenatal ultrasonography but not on physical examination Genetic disorders (2) Secondary end points Weight, length, and head circumference at birth, one month, six months and 12 months. HIV-1 drug resistance mutations among infants who acquire HIV-1 infection

Delivery prior to 37 completed weeks of gestation Stillbirth or intrauterine fetal demise (≥20 weeks) Spontaneous abortion (<20 weeks) Ectopic pregnancy Intrapartum hemorrhage Postpartum hemorrhage Non-reassuring fetal status Chorioamnionitis Hypertensive disorders of pregnancy Gestational diabetes Intra-uterine growth restriction