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. 2018 May 29;9(41):26491–26506. doi: 10.18632/oncotarget.25474

Figure 2. Effects of ponatinib, JQ1 and dBET1 on late apoptosis of colon, breast and ovarian cancer cells.

Figure 2

HCT116, HT29, MCF7, SKBR3, A2780 and SKOV3 cells were incubated in control medium (co) or in medium containing various concentrations of ponatinib (A), JQ1 (B) or dBET1 (C) at 37° C for 48 hours. Then, cells were examined by flow cytometry to determine the percentage of late apoptotic, active caspase-3 positive cells. Results represent the mean ± SD of 3 independent experiments. The level of significance was determined by ANOVA followed by Scheffe test. Asterisk (*): p < 0.05 compared to control.