Table 1. Top 10 most abundant mouse-derived proteins detected solely in tumor stroma.
| Mouse UniProt Acc # |
Gene | Protein Description | PSMs | Biological process | Reference |
|---|---|---|---|---|---|
| Q99P91 | Gpnmb | Transmembrane glycoprotein NMB (DC-HIL) | 344 | Negative regulation of immune response | Blood. 2007 May 15;109(10):4320-7. |
| P08101 | Fcgr2 | Low affinity immunoglobulin gamma Fc region receptor II | 151 | Negative regulation of immune response | Immunity. 2017 Apr 18;46(4):577-586. |
| Q9D7Z6 | Clca1 | Calcium-activated chloride channel regulator 1 | 132 | Inflammatory - immune response | PLoS One. 2013 Dec 12;8(12):e83130 |
| Q9DBP0 | Slc34a2 | Sodium-dependent phosphate transport protein 2B | 124 | Ab-drug conjugate -cancer immunotherapy | Clin Cancer Res. 2015 Nov 15;21(22):5139-50. |
| P01896 | N/A | H-2 class I histocompatibility antigen, alpha chain | 120 | Negative regulation of immune response | Bull Acad Natl Med. 2014 Apr-May;198(4-5):801-11. |
| P70232 | Chl1 | Neural cell adhesion molecule L1-like protein | 67 | Promotes tumorigenicity and metastasis | Clin Cancer Res. 2012 Apr 1;18(7):1914-24. |
| Q6R5N8 | Tlr13 | Toll-like receptor 13 | 65 | Innate immune response | J Immunol. 2012 Sep 15;189(6):2717-21. |
| Q62192 | Cd180 | CD180 antigen | 59 | Immune response | J Exp Med. 2000 Jul 3;192(1):23-9. |
| Q9WUL5 | Pdcd1lg2 | Programmed cell death 1 ligand 2 (PD-L2) | 36 | Negative regulation of immune response | J Immunol. 2007 May 1;178(9):5552-62. |
| Q99NH8 | Trem2 | Triggering receptor expressed on myeloid cells 2 | 34 | Immune response | Oncotarget. 2016 May 17;7(20):29620-34. |