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. 2018 May 25;9(40):26259–26278. doi: 10.18632/oncotarget.25447

Figure 4. Regulation of transcriptional activity by p27 is mediated by its association with different transcriptional regulators.

Figure 4

To regulate transcription p27 associates with different transcriptional regulators including TFs as p130/E2F4 complexes, Ap2, Pax4, Ets1, AHR, Neurogenein-2 (Ngn2), MyoD and Pax5. It also interacts with the transcriptional co-activator and acetyltransferase p300/CBP associating factor (PCAF). The biological functions putatively regulated by these TFs and p27 are indicated.