FIG. 3.
RCCS affects cardiogenic and neurogenic programs by altering the Wnt and bone morphogenetic protein (BMP) signaling pathways. (A) The 10 process networks most significantly affected (statistically significant), based on microarray enrichment analysis of day 10 iPSCkit-Cre-derived EBs, grown under SC or RCCS. (B) The 10 GO processes most significantly affected, based on microarray enrichment analysis of day 10 iPSCkit-Cre-derived EBs, grown under SC or RCCS. (n = 2 biological replicates for day 10 RCCS, and n = 3 biological replicates for day 10 SC). GO, gene ontology.