FIG. 4.
Abnormal BMP/TGF-β and Wnt/β-catenin following transition from RCCS to SC. (A) The 10 signaling pathways most significantly affected based on microarray enrichment analysis of day 21 iPSCkit-Cre-derived EBs, grown continuously under SC or following transfer from RCCS to SC on day 10. (B) The 10 GO processes most significantly affected, based on microarray enrichment analysis of day 21 iPSCkit-Cre-derived EBs, grown continuously under SC or following transfer from RCCS to SC on day 10 (n = 3 biological replicates per group).