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. 2018 Jun 7;10:257–266. doi: 10.2147/IJWH.S157056

Table 2.

Pearl Index and the exposure time during estradiol valerate/dienogest treatment in the full analysis set (n=954)

Age group, years PI type Total exposure, days Relevant exposure, WY Number of pregnancies PI 95% CI
Overall Adjusted PI 299,752 760.35 3 0.39 0.08–1.15
 18–35 197,503 500.36 3 0.60 0.12–1.75
 36–50 102,249 259.99 0 0.00 0.00–1.42
Overall Unadjusted PI 299,752 796.34 5 0.63 0.20–1.47
 18–35 197,503 524.38 4 0.76 0.21–1.95
 36–50 102,249 271.97 1 0.37 0.01–2.05

Abbreviations: PI, Pearl Index; WY, woman-year.