Figure 1.

Memory function created by embedding bistable neurons in feedfoward networks. A network is modeled on the dentate gyrus, which contains a set of bistable excitatory neurons (semilunar granule cells) (Larimer & Strowbridge 2010, Williams et al. 2007) that generate divergent projections onto downstream cells (hilar neurons in the dentate gyrus). Different input patterns can trigger bistable responses in different subsets of bistable cells, leading to different combinations of synaptic input barrages in the downstream neurons. Which input was presented can be determined by monitoring changes in the synaptic tone in a small subgroup of downstream neurons (as in Hyde & Strowbridge 2012 and Larimer & Strowbridge 2010).