Table 1. Clinicopathological parameters in 369 locally advanced esophageal squamous cell carcinoma patients with/without supraclavicular lymph node (SCLN) metastasis receiving curative CCRT.
Characteristics | SCLN metastasis group (N = 70) | Non-SCLN metastasis group (N = 299) | P value |
---|---|---|---|
Age | |||
< 60 years | 54 (77%) | 215 (72%) | 0.38 |
≥ 60 years | 16 (23%) | 84 (28%) | |
Gender | |||
Male | 67 (96%) | 291 (97%) | 0.48 |
Female | 3 (4%) | 8 (3%) | |
Performance status | |||
0–1 | 59 (84%) | 262 (88%) | 0.46 |
2 | 11 (16%) | 37 (12%) | |
T status | |||
1 + 2 + 3 | 33 (47%) | 132 (44%) | 0.65 |
4 | 37 (53%) | 167 (56%) | |
N status | |||
0 + 1 + 2 | 31 (44%) | 262 (88%) | <0.001* |
3 | 39 (46%) | 37 (12%) | |
Grade | |||
1 | 10 (14%) | 32 (11%) | 0.40 |
2 + 3 | 60 (86%) | 267 (89%) | |
Location | |||
Upper | 35 (50%) | 87 (29%) | 0.001* |
Middle + Lower | 35 (50%) | 212(71%) | |
Salvage operation | |||
Yes | 11 (16%) | 49 (16%) | 0.89 |
No | 59 (84%) | 250 (84%) | |
Radiotherapy dose | |||
50–50.4 Gy | 67 (96%) | 276 (92%) | 0.32 |
< 50Gy | 3 (4%) | 23 (8%) | |
Cycles of chemotherapy | |||
1 | 11 (16%) | 31 (10%) | 0.21 |
2 | 59 (84%) | 268 (90%) | |
Lower | 3 (9%) | 95 (26%) |
SCLN: Supraclavicular lymph node; CCRT: concurrent chemoradiotherapy
*Statistically significant.