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. 2018 Jun 11;13(6):e0198800. doi: 10.1371/journal.pone.0198800

Table 1. Clinicopathological parameters in 369 locally advanced esophageal squamous cell carcinoma patients with/without supraclavicular lymph node (SCLN) metastasis receiving curative CCRT.

Characteristics SCLN metastasis group (N = 70) Non-SCLN metastasis group (N = 299) P value
Age
    < 60 years 54 (77%) 215 (72%) 0.38
    ≥ 60 years 16 (23%) 84 (28%)
Gender
    Male 67 (96%) 291 (97%) 0.48
    Female 3 (4%) 8 (3%)
Performance status
    0–1 59 (84%) 262 (88%) 0.46
    2 11 (16%) 37 (12%)
T status
    1 + 2 + 3 33 (47%) 132 (44%) 0.65
    4 37 (53%) 167 (56%)
N status
    0 + 1 + 2 31 (44%) 262 (88%) <0.001*
    3 39 (46%) 37 (12%)
Grade
  1 10 (14%) 32 (11%) 0.40
    2 + 3 60 (86%) 267 (89%)
Location
    Upper 35 (50%) 87 (29%) 0.001*
    Middle + Lower 35 (50%) 212(71%)
Salvage operation
    Yes 11 (16%) 49 (16%) 0.89
    No 59 (84%) 250 (84%)
Radiotherapy dose
    50–50.4 Gy 67 (96%) 276 (92%) 0.32
    < 50Gy 3 (4%) 23 (8%)
Cycles of chemotherapy
    1 11 (16%) 31 (10%) 0.21
    2 59 (84%) 268 (90%)
    Lower 3 (9%) 95 (26%)

SCLN: Supraclavicular lymph node; CCRT: concurrent chemoradiotherapy

*Statistically significant.