Table 1.
Characteristics of the participants
| Characteristics of the participants | Tertile 1, n=257, 3–10 ng/L | Tertile 2, n=231, 11–16 ng/L | Tertile 3, n=234, ≥17 ng/L | P-value |
|---|---|---|---|---|
| Baseline characteristics | ||||
| Age (years) | 79.77±6.13 | 83.04±5.24 | 84.73±5.34 | <0.001 |
| Male gender | 140 (54.5) | 152 (65.8) | 181 (77.4) | <0.001 |
| Body mass index (kg/m2) | 23.39±3.30 | 23.62±3.30 | 23.80±3.29 | 0.376 |
| Heart rate (beats/min) | 72.31±12.08 | 74.23±13.22 | 75.23±13.51 | 0.058 |
| Comorbidities | ||||
| CAD | 64 (24.9) | 78 (33.8) | 91 (38.9) | 0.004 |
| Hypertension | 194 (75.5) | 182 (78.8) | 203 (86.8) | 0.006 |
| DM | 77 (30) | 97 (42) | 99 (42.3) | 0.005 |
| Cerebral infarction | 145 (56.4) | 136 (58.9) | 154 (65.8) | 0.092 |
| COPD | 37 (14.4) | 42 (18.2) | 59 (25.2) | 0.009 |
| CKD | 43 (16.7) | 49 (21.2) | 84 (35.9) | <0.001 |
| AF | 30 (11.7) | 45 (19.5) | 31 (13.2) | 0.039 |
| Number of comorbidities | ||||
| ≤1 | 78 (30.4) | 46 (19.9) | 31 (13.2) | <0.001 |
| 2–3 | 137 (53.3) | 119 (51.5) | 112 (47.9) | 0.258 |
| ≥4 | 42 (16.3) | 66 (28.6) | 91 (38.9) | <0.001 |
| Biochemistry | ||||
| NT-proBNP (pg/mL) | 171 (80.06, 402.90) | 297 (147.10, 606.50) | 562.1 (225.40, 1,174.00) | <0.001 |
| eGFR (mL/min·1.73 m2) | 78.73±22.69 | 76.48±23.59 | 67.86±27.54 | <0.001 |
| Hb (g/L) | 131.35±15.53 | 128.84±19.39 | 123.44±21.92 | <0.001 |
| FBG (mmol/L) | 5.41±1.30 | 5.66±1.96 | 5.83±2.24 | 0.041 |
| Echocardiography | ||||
| LVEF (%) | 59.97±3.40 | 59.33±4.00 | 57.89±3.34 | <0.001 |
| LVMI (g/m2) | 117.90±31.90 | 123.73±37.40 | 128.42±40.64 | 0.008 |
Notes: Data are presented as number (%) or mean±SD or median (interquartile range). P-value is for comparison by ANOVA or Kruskal–Wallis tests.
Abbreviations: CAD, coronary artery disease; DM, diabetes mellitus; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; AF, atrial fibrillation; NT-proBNP, amino-terminal pro-brain natriuretic peptide; eGFR, estimated glomerular filtration rate; Hb, hemoglobin; FBG, fasting blood glucose; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index.