Table S4.
Optimal cut-off value and corresponding sensitivity and specificity of GRACE and CHA2DS2-VASc scores
| Predictive model (optimal cut-off value) | Diagnostic accuracy |
|---|---|
| Overall cohort | |
| GRACE risk score (>118) | Specificity: 51.3% Sensitivity: 89.8% |
| CHA2DS2-VASc score (>2) | Specificity: 60.4% Sensitivity: 69.4% |
| Sex category | |
| Male | |
| GRACE risk score (>116) | Specificity: 54.2% Sensitivity: 86.2% |
| CHA2DS2-VASc score (>2) | Specificity: 68.2% Sensitivity: 55.2% |
| Female | |
| GRACE risk score (>140) | Specificity: 58.0% Sensitivity: 80.0% |
| CHA2DS2-VASc score (>3) | Specificity: 45.7% Sensitivity: 75.0% |
| GRACE risk score stratification | |
| Low-risk (≤125) | |
| GRACE risk score (>112) | Specificity: 67.9% Sensitivity: 83.3% |
| CHA2DS2-VASc score (>0) | Specificity: 13.9% Sensitivity: 100% |
| Intermediate-risk (126 to 154) | |
| GRACE risk score (>136) | Specificity: 50.5% Sensitivity: 71.4% |
| CHA2DS2-VASc score (>3) | Specificity: 64.0% Sensitivity: 61.9% |
| High-risk (≥155) | |
| GRACE risk score (>170) | Specificity: 55.6% Sensitivity: 87.5% |
| CHA2DS2-VASc score (≤3) | Specificity: 74.1% Sensitivity: 50.0% |
Abbreviation: GRACE, Global Registry of Acute Coronary Events.