Table S3.
Baseline characteristics of included patients based on GRACE risk score stratification
| Variables | Low-risk (GRACE risk score ≤125)
|
Intermediate-risk (GRACE risk score 126–154)
|
High-risk (GRACE risk score ≥155)
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| SR (n=274) | NOAF (n=12) | p-value | SR (n=111) | NOAF (n=21) | p-value | SR (n=54) | NOAF (n=16) | p-value | |
| Age (years) | 57.2±8.3 | 61.3±7.5 | 0.09 | 72.9±8.1 | 75.7±6.5 | 0.13 | 80.4±8.4 | 81.4±9.2 | 0.68 |
| Female (%) | 26 (9.5) | 1 (8.3) | 1.00 | 33 (29.7) | 11 (52.4) | 0.04 | 22 (40.7) | 8 (50.0) | 0.51 |
| Hypertension (%) | 164 (59.9) | 9 (75.0) | 0.45 | 72 (64.9) | 16 (76.2) | 0.31 | 44 (81.5) | 8 (50.0) | 0.03 |
| Diabetes (%) | 84 (30.7) | 4 (33.3) | 1.00 | 42 (37.8) | 7 (33.3) | 0.70 | 23 (42.6) | 6 (37.5) | 0.72 |
| Dyslipidemia (%) | 174 (63.5) | 9 (75.0) | 0.61 | 54 (48.6) | 13 (61.9) | 0.27 | 25 (48.1) | 11 (68.8) | 0.15 |
| Smoker (%) | 179 (65.3) | 5 (41.7) | 0.17 | 41 (36.9) | 4 (19.0) | 0.11 | 13 (24.1) | 3 (18.8) | 0.92 |
| CKD (%) | 23 (8.4) | 4 (33.3) | 0.02 | 32 (28.8) | 6 (28.6) | 0.98 | 27 (50.0) | 6 (37.5) | 0.38 |
| CHF (%) | 26 (9.5) | 4 (33.3) | 0.03 | 22 (19.8) | 6 (28.6) | 0.54 | 22 (40.7) | 5 (31.2) | 0.49 |
| Previous stroke/TIA (%) | 18 (6.6) | 0 | 0.76 | 12 (10.8) | 4 (19.0) | 0.49 | 15 (27.8) | 1 (6.2) | 0.14 |
| Previous vascular disease (%) | 20 (7.3) | 1 (8.3) | 1.00 | 15 (13.5) | 1 (4.8) | 0.45 | 3 (5.6) | 3 (18.8) | 0.25 |
| Previous MI (%) | 12 (4.4) | 0 | 1.00 | 7 (6.3) | 0 | 1.00 | 2 (3.7) | 2 (12.5) | 0.22 |
| Previous PCI (%) | 17 (6.2) | 1 (8.3) | 1.00 | 10 (9.0) | 1 (4.8) | 0.83 | 4 (7.4) | 3 (18.8) | 0.39 |
| On-admission Killip class (%) | 0.70 | 0.65 | 0.92 | ||||||
| I | 254 (92.7) | 12 (100) | 88 (79.3) | 17 (81.0) | 21 (38.9) | 1 (6.3) | |||
| II | 20 (7.3) | 0 | 19 (17.1) | 4 (19.0) | 17 (31.5) | 7 (43.8) | |||
| III–IV | – | – | 4 (3.6) | 0 | 16 (29.6) | 8 (50.0) | |||
| On-admission HFa | 20 (7.3) | 0 | 0.70 | 23 (20.7) | 4 (19.0) | 1.00 | 33 (61.1) | 15 (93.8) | 0.01 |
| On-admission SBP (mmHg) | 135.8±21.8 | 131.5±27.1 | 0.51 | 131.3±20.3 | 135.0±22.9 | 0.46 | 121.4±26.1 | 114.8±24.7 | 0.37 |
| On-admission HR (bpm) | 79.9±15.9 | 90.0±17.2 | 0.03 | 79.7±17.5 | 74.6±17.5 | 0.22 | 84.8±19.9 | 90.6±23.2 | 0.33 |
| Cardiac arrest (%) | 1 (0.4) | 0 | 1.00 | 2 (1.8) | 1 (4.8) | 0.41 | 6 (11.1) | 1 (6.2) | 0.92 |
| CHA2DS2-VASc score | 1.6±1.2 | 2.1±1.2 | 0.20 | 3.2±1.4 | 3.9±1.5 | 0.03 | 4.5±1.7 | 3.8±1.5 | 0.13 |
| GRACE risk score | 102.4±15.9 | 113.6±15.4 | 0.02 | 137.8±7.8 | 140.3±7.1 | 0.18 | 175.1±19.4 | 188.1±25.8 | 0.03 |
| In-hospital death (%) | 5 (1.8) | 1 (8.3) | 0.61 | 2 (1.8) | 2 (9.5) | 0.12 | 12 (22.2) | 4 (25.0) | 1.00 |
| Hospitalization (days) | 6.8±3.0 | 8.8±3.1 | 0.03 | 8.4±5.3 | 9.7±5.1 | 0.30 | 7.9±5.1 | 13.6±4.5 | <0.01 |
Notes:
a
On-admission Killip class >I. Data presented as n (%) or mean ± SD.
Abbreviations: CHF, chronic heart failure; CKD, chronic kidney dysfunction; GRACE, Global Registry of Acute Coronary Events; HF, heart failure; HR, heart rate; MI, myocardial infarction; NOAF, new-onset atrial fibrillation; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; SR, sinus rhythm; TIA, transient ischemic attack.