Figure 1.

FDA-approved drugs for melanoma treatment. Dacarbazine was the first drug approved, in 1974, followed by interferon α-2b, interleukin-2, and ontak in the 1990s. Between 2011 and 2015, 10 therapies were approved, including selective inhibitors, antibodies, and combined targeted therapies.

Abbreviation: FDA, US Food and Drug Administration.