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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Mol Immunol. 2018 May 19;99:154–162. doi: 10.1016/j.molimm.2018.05.007

Figure 4. TNFAIP8L2 negatively regulates gene signatures of inflammation and lipid biosynthesis.

Figure 4

Bone marrow-derived macrophages from either wild type mice or Tnfaip8l2 gene knockout (KO) mice (pooled sample of 5 in each group) were challenged with LPS (100 ng/mL) for 1 hour and microarray was performed. A. ClueGO pathway enrichment analysis of the genes that are changed by more than 1.5-folds in Tnfaip8l2 gene KO mice. B. Enrichment plots from Gene Set Enrichment Analysis (GSEA) of “interferon signaling” and “cholesterol biosynthesis”.