Table 2.
Peptide | Peptide RTa | Polar SASAb | Apolar SASA | Percentage of Apolar SASA | Net chargec |
---|---|---|---|---|---|
min | % | ||||
CcoTx-I | 26.5 | 1230 | 1653 | 57 | 3 |
CcoTx-II | 27.0 | 1083 | 1736 | 62 | 4 |
GpTx-I | 24.1 | 1187 | 1873 | 61 | 4 |
GsMTx-IV | 35.4 | 1023 | 2010 | 66 | 5 |
HnTx-IV | 20.7 | 1245 | 1604 | 56 | 4 |
HwTx-IV | 26.0 | 1289 | 1888 | 59 | 4 |
PaurTx-III | 26.9 | 1046 | 1914 | 65 | 4 |
ProTx-I | 32.7 | 1165 | 1830 | 61 | 2 |
SgTx-I | 35.7 | 1001 | 1823 | 65 | 2 |
a Retention time of peptides obtained by analytical HPLC (1%/min gradient of 0–60% solvent B at a flow rate of 0.3 ml/min).
b SASA calculated using GETAREA: http://curie.utmb.edu/getarea.html. (Please note that the JBC is not responsible for the long-term archiving and maintenance of this site or any other third party hosted site.)
c Net charge was calculated at pH 7.4 using pKa values from Propka (jensengroup) (59).