TABLE 5.

SNOT-22 total score adjusted mixed-effects model—difference in change at 12 months between LMCTS quartiles with 95% CIs

	First Q (1–8)	Second Q (9–12)	p	Third Q (13–16)	p	Fourth Q (17–24)	p
SNOT-22 total score	Ref. group	−4.4 (−10.7 to 1.9)	0.171	−6.2 (−13.1 to 0.7)	0.078	−13.1 (−20.2 to −6.0)	<0.001
Subscales
Rhinologic (0–35)	—	−2.4 (−4.5 to −0.3)	0.024	−3.0 (−5.3 to −0.7)	0.011	−5.3 (−7.7 to −3.0)	<0.001
Extranasal (0–15)	—	−1.4 (−2.7 to −0.1)	0.030	−1.4 (−2.8 to 0.05)	0.058	−2.1 (−3.5 to −0.6)	0.005
Ear/Facial (0–25)	—	−0.6 (−1.9 to 0.8)	0.397	−0.4 (−1.9 to 1.1)	0.596	−2.0 (−3.6 to −0.5)	0.009
Psychological (0–35)	—	−0.9 (−3.4 to 1.6)	0.466	−1.1 (−3.8 to 1.6)	0.436	−3.1 (−5.9 to −0.3)	0.030
Sleep (0–25)	—	−0.3 (−2.5 to 1.9)	0.799	−0.8 (−3.2 to 1.6)	0.533	−2.5 (−4.9 to 0.01)	0.051

^*Adjusted for the effect of both nasal polyps and previous functional endoscopic sinus surgery (revision vs primary).

CI = confidence interval; LMCTS = Lund-Mackay computed tomography score; Q =quartile; SNOT-22 = 22-item Sino-Nasal Outcomes Test.