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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Orthop Res. 2018 Jan 3;36(6):1614–1623. doi: 10.1002/jor.23831

Figure 1. Increased S. aureus proliferation in obese/T2D mice following orthopaedic infection.

Figure 1

Mice were fed a high fat-diet to induce obesity/T2D or a control diet for 3 months. Mice were then infected with a trans-tibial pin pre-coated with S. aureus USA300 lac::lux. A. At 21 days post infection, tibia were harvested and S. aureus CFUs were quantitated. n ≥ 9. B. Time course of bioluminescent signal emitted at the implant site from luminescent S. aureus containing the lux a-e operon indicating S. aureus proliferation. n = 5. C. Area under the curve for B. * P<.05, ** p<.01. Unpaired student T test for A and C. Two way Anova was used for B with Tukey post-hoc test. In A, C, each point represents one mouse.