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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Psychoneuroendocrinology. 2018 Apr 22;94:1–10. doi: 10.1016/j.psyneuen.2018.04.019

Fig 6. Kynurenine administration reduces microglial activation state.

Fig 6

Fig 6

BV2 microglia were treated with saline or LPS (100 ng/mL), then immediately followed by treatment with kynurenine (vehicle, 0.048, 0.48, 4.8, 48, 480 μM). After 4 h, cells were collected for qPCR analysis to determine expression of: A, Il1b (interleukin-1-b); B, Il6 (interlekin-6); C, Tnf (tumor necrosis factor-a); D, Il10 (interleukin-10); E, Nos2 (inducible nitric oxide synthase). Data were analyzed using two-way ANOVA followed by Holm Sidak post hoc analysis.