Table 1. Patient Characteristics of DSAPosAMRNeg and DSAPosAMRPos Populations.
Categorical variables were expressed as a percentage and a number, while quantitative variables were expressed either as median with 25–75 interquartile range (IQR) unless specify as § for mean±SD. Fisher or Chi-square tests were used for categorical variables. Mann-Whitney test was used for continuous variables. Abbreviations: AR: acute cellular rejection; BMI: Body Mass Index; CF: Cystic Fibrosis; ECMO: extra corporeal Membrane Oxygenation; EVLP: ex vivo lung preconditioning; GERD: gastro-esophagial reflux; ILD: Interstitial Lung Disease; LAS: Lung Allocation Score; PGD3: Primary Graft Dysfunction grade 3.
| Clinical Variable | DSAPosAMRNeg (n=23) | DSAPosAMRPos (n=15) | p value |
|---|---|---|---|
| Recipient Age (years) | 38.8 (28.9–50) | 33.2 (21.6–56.5) | 0.45 |
| Underlying Disease (Emphysema/ILD/CF/others) | 7/5/9/2 | 3/4/6/2 | 0.88 |
| Gender (F) | 16 | 6 | 0.1 |
| BMI | 19.5 (17.6–22.4) | 20.3 (17.9–30) | 0.38 |
| LAS | 36.40 (32.84–45.40) | 35.70 (33.30–41.10) | 0.95 |
| Donor Age (years) | 49 (40–57) | 48 (37–62) | 0.71 |
| Donor P/F | 372 (307–433) | 380 (323–424) | 0.67 |
| Ischemia Duration (minutes) | 380 (270–442) | 379 (340–474) | 0.42 |
| HELT | 4 (16%) | 2 (13%) | 1 |
| Peri-op ECMO | 9 (40%) | 9 (60%) | 0.32 |
| EVLP | 7 (32%) | 1 (6%) | 0.11 |
| PGD3 at H72 | 8 (32%) | 1 (6%) | 0.06 |
| CMV DR (D−R−/D+R+/D−R+/D+R+) | 4/9/4/6 | 3/5/6/1 | 0.29 |
| HLA Mismatch § | 6.09±1.02 | 6.93±0.96 | 0.03 |
| Induction | 17 (68%) | 10 (66%) | 1 |
| AR at M12 § | 0.78±0.9 | 2±1.5 | 0.01 |
| GERD | 16 (84%) | 6 (75%) | 0.62 |