Table 8. Characteristics of various of animal models of AAA.
Animal models | CaCl 2 | Elastase | Angiotensin 2 |
---|---|---|---|
Mechanism | Calcification and inflammation | Calcification and inflammation | Inflammation |
Rupture | No | Yes | Yes |
Intraluminal t hrombosis | No | Yes | No |
Need for major surgery | Yes | Yes | No |
Abbreviations: AAA, abdominal aortic aneurysm; CaCl 2 , calcium chloride.