Table 1.
Characteristics of the Patients.
| Variables | Group RS(n=15) (n=15) |
Group S (n=47) |
p value |
|---|---|---|---|
| Age (median, IQR) | 75 (61-78) | 68 (62-76) | 0.30 |
| Sex (Male/Female) | 9 /6 | 40 /7 | 0.048 |
| Etiology (HBV/HCV/ NBNC) | 2/8/5 | 7 /33 /7 | 0.88 |
| Child-Pugh score (5/6) | 11 /4 | 25/22 | 0.16 |
| Metastastic lesions | |||
| Lung | 2 | 12 | 0.3 |
| Bone | 6 | 17 | 0.84 |
| Lymph node | 7 | 15 | 0.3 |
| Adrenal gland | 1 | 4 | 0.78 |
| Maxium diameter of metastastic lesions (median, IQR) (mm) | 30 (18-43) | 24 (20-34.3) | 0.30 |
| Macrovascular invasion | 4 | 18 | 0.54 |
| Portal vein invasion (1/2/3/4) | 0/0/2/0 | 0/9/5/2 | 0.40 |
| Hepatic vein invasion (1/2/3) | 0/0/2 | 0/1/3 | 0.44 |
| Concomitant intrahepatic lesions | 10 | 38 | 0.30 |
| Initial dose of sorafenib [800/400/200 (mg)] | 1/9/5 | 11/28/8 | 0.21 |
| AFP (median, IQR) (ng/mL) | 17.2 (6.4-2,672) | 129 (13-469) | 0.63 |
| AFP-L3 (median, IQR) (%) | 30 (0.38-61.9) | 15 (1.4-64.7) | 0.61 |
| DCP (median, IQR) (mAu/mL) | 228 (24.5-1,255) | 180 (26.5-7,708) | 0.4 |
IQR: interquartile range, HBV: hepatitis B, HCV: hepatitis C, NBNC: non hepatitis B and non hepatitis C, AFP: α-fetoprotein, AFP-L3: Lens culinaris agglutinin-reactive fraction of AFP, DCP: des-γ-carboxy prothrombin