. Author manuscript; available in PMC: 2018 Jun 12.

Published in final edited form as: J Med Chem. 2017 Nov 22;60(23):9739–9756. doi: 10.1021/acs.jmedchem.7b01199

Table 3.

Protective Effect of Ring Analogues of 1 to Ameliorate Etoposide-Induced Apoptosis in PC12 Cells (n = 3, Percentage Cell Viability Represented As Mean ± SEM

Compound	% Viability (3 μM)	MPO Score
Vehicle	52.13±1.13
1	79.50 ± 3.22	4.50
2	73.92 ± 8.03	4.50
19	109.51 ± 7.90	5.00
20	53.80 ± 1.14	4.79