Table 1.

Summary of RNA expression data sets used in this analysis.

Data Set	Species	Data Type	GEO accession	# AST	# END	# MIC	# NEU	# MOL	# OPC	Covariates
Darmanis	Human	Single-cell	GSE67835	62	20	16	131	38	18	Total Features
Zhang (2016)	Human	Cell population	GSE73721	12	2	3	1	5	—	—
Zhang (2015)	Mouse	Cell population	GSE52564	2	2	2	2	2	2	—
Zeisel	Mouse	Single-cell	GSE60361	129	137	33	1519	484	—	Total Features, Tissue, Age
Tasic	Mouse	Single-cell	GSE71585	50	21	22	1465	42	24	Total Features

The sample size for each cell type, as well as the covariates included in the differential expression model, for each of the data sets used in this meta-analysis. Note that these numbers are calculated subsequent to cleaning and combining of cell populations originally annotated in each of the data sets, as described in the Methods. A dash indicates that a cell type was not present in that data set. AST = astrocyte, END = endothelial cell, MIC = microglia, NEU = neuron, MOL = mature oligodendrocyte, OPC = oligodendrocyte precursor cell.