Fig. 1.

Estimated correlation of genetic effects of cis-eQTLs between tissues. We estimated r_b between brain regions, between brain and blood tissues, and between data sets. The top-associated cis-eQTLs (one for each gene) were selected from GTEx-muscle at P_eQTL < 5 × 10⁻⁸. Shown in each cell is the estimate of r_b with its standard error given in the parentheses (Methods). In the Braineac data, the eQTLs effect sizes were estimated from gene expression levels averaged across 10 brain regions