Table 1.
Characteristics of the POAG cases and controls from GERA cohort
| Controls | Cases | ||
|---|---|---|---|
| Total | N (proportion that are cases) | 58 426 | 4 986 (7.9%) |
| Age (years) | Mean ± SD | 69.7 ± 13.0 | 79.6 ± 9.4 |
| Sex | Women - N (proportion that are cases) | 35 193 | 2 689 (7.1%) |
| Men - N (proportion that are cases) | 23 233 | 2 297 (9.0%) | |
| NTG cases | N | — | 743 |
| Controls with an OHTN diagnosis | N | 881 | — |
| Median IOP | Mean ± SD | 14.9 ± 2.6 | 15.5 ± 2.9 |
| Non-Hispanic white | N (proportion that are cases) | 48 065 | 3 836 (7.4%) |
| Age (years), mean ± SD | 70.7 ± 12.5 | 80.5 ± 9.0 | |
| Sex, number of women/men | 28 798/19 266 | 2 115/1 721 | |
| Hispanic/Latino | N (proportion that are cases) | 4 778 | 411 (7.9%) |
| Age (years) Mean ± SD | 65.0 ± 14.4 | 75.5 ± 10.1 | |
| Sex, number of Women / Men | 2 965/1 813 | 218/193 | |
| East Asian | N (proportion that are cases) | 4 034 | 441 (9.9%) |
| Age (years), mean ± SD | 64.6 ± 14.4 | 76.6 ± 10.0 | |
| Sex, number of women/men | 2 453/1 581 | 202/239 | |
| African-American | N (proportion that are cases) | 1 549 | 298 (16.1%) |
| Age (years), mean ± SD | 66.7 ± 13.3 | 77.7 ± 9.3 | |
| Sex, number of women/men | 976/573 | 154/144 |
N number, SD standard deviation, POAG primary open-angle glaucoma, NTG normal tension glaucoma, OHTN ocular hypertension, defined as participants who had a diagnosis of ocular hypertension but have no diagnosis of any type of glaucoma, IOP intraocular pressure, Age age at last vision exam