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Prevalence of amino acid variants in 165 NS5B genotype 1b Japanese patients at baseline and LDV/SOF treatment outcome in clinical trial.
| Amino acid substutition in NS5B region | Prevalence (n/N) | LDV/SOF SVR rate |
|---|---|---|
| A207T | 33.9 (56/165) | 100% |
| A218S | 67.9 (112/165) | 100% |
| C316N | 55.8 (92/165) | 100% |
| Q464E | 54.5 (90/165) | 100% |
| A207T/A218S/C316N/Q464E | 32.1 (53/165) | 100% |
