Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Genotype 1b HCV Replicon Assay for Sofosbuvir. The ratios of EC50 values of the mutant HCV strains relative to that of wild-type HCV strain were shown as mean ± SD.
| Amino acid substitution in NS5B region | The Ratios of SOF EC50 values relative to that of wild-type HCV |
|---|---|
| A207T | 0.83 ± 0.23 |
| A218S | 1.07 ± 0.24 |
| C316N | 0.99 ± 0.23 |
| Q464E | 0.87 ± 0.17 |
| A218S/C316N | 0.85 ± 0.22 |
| A207T/A218S/C316N/Q464E | 1.11 ± 0.04 |
