Skip to main content
. 2018 Jun 11;8:8829. doi: 10.1038/s41598-018-27200-y

Figure 2.

Figure 2

Cxcl16 expression in acute necrotizing pancreatitis. (A) Protocols of acute necrotizing pancreatitis by repeated injection of cerulein. Cerulein (100 ug/kg) was injected every 1 h 8 times on 2 consecutive days into C57BL/6 mice. Four to five mice were sacrificed at the indicated time points. (B) Serum amylase level and (C) pathology score of the respective time-points. (D) H&E sections in the pancreas of mice treated with acute necrotizing pancreatitis regimen at 0, 9, 24, and 33 h, respectively. The section at 33 h shows disrupted acinar architecture, vacuolization and necrosis of acinar cells, and inflammatory cell infiltration. (E) Pancreatic mRNA expressions of Cxcl16, Tnfα, Il6, and Cxcl2 were determined by quantitative RT-PCR analysis. *p < 0.05 Results were shown as mean ± SD.