Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sequence analysis the humanization of murine antibody. (A)CDR of heavy chain; (B) CDR of light chain; (C) Molecular docking of mouse monoclonal antibody(E12) and (D) humanized monoclonal antibody(H3L3) with bFGF. (E)The number of base substitutions in light chain (L chain) and heavy chain (H chain). (F) The degree of humanization among L chains and H chains in WT(E12), H1L1, H2L2 and H3L3. WT represents the murine monoclonal antibody; light chain(White); heavy chain(gray).
