Skip to main content
. 2018 Apr 30;9(11):2003–2011. doi: 10.7150/jca.24255

Figure 4.

Figure 4

The inhibitory effects of H3L3 on the tumor growth in vivo. (A) Changes in tumor volume during the days of the experiment in different groups. (B) Photographs of xenograft tumors formed from H460 cells in different experiment groups. (C) Histogram showing the volume of different experiment groups. (D) Histogram revealing the inhibition rate of tumor growth in different experiment groups compared to control (PBS). Cisplatin is the positive group. (E) Weight of BABL/c-nu mice were measured every three days during the experiments in different groups. The data are presented as means ± SD from five mice. (F)Tumor xenografts established from H460 cells are immunostained for CD31 and analysed for micro-vessel density, treated with H3L3(25mg/kg), H3L3(12.5mg/kg), H3L3(6.25mg/kg), Cisplatin(2.50mg/kg) and PBS, respectively. (G)Quantification of the micro- vessel density. Data are presented as the mean ± SD of three independent experiments performed in triplicate. ***P<0.001.