Table 2.

Promoter methylation frequency of p16, APC, MGMT, TIMP3 and CDH1 genes in tumour and surgical margin in oral cavity patients

Gene	Tumour			Margin			p-value
	Total	Methylation	Frequency (%)	Total	Methylation	Frequency (%)	P
p16	75	44	58.67	75	38	50.67	0.325
APC	75	37	49.33	75	29	41.33	0.188
MGMT	75	44	58.67	75	28	37.33	< 0.01
TIMP3	75	38	50.67	75	32	42.67	0.326
CDH1	75	43	57.33	75	19	25.33	< 0.001