Table 3.

Prognostic factors for survival outcomes from univariate and multivariate analyses.

Variate	Category	p value
		Univariate analysis				Multivariate analysis
		LRRFS	DMFS	PFS	OS	LRRFS	DMFS	PFS	OS
Age (years)	<50	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
	≥ 50	0.103	0.781	0.118	0.177	0.097	0.851	0.106	0.185
Sex	Male	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
	Female	0.963	0.654	0.860	0.873	0.871	0.615	0.736	0.777
T stage*	T1	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
	T2	0.093	0.665	0.095	0.319	0.121	0.742	0.114	0.317
N stage*	N0	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
	N1	0.098	0.340	0.375	0.418	0.477	0.972	0.850	0.387
Regimen	IMRT alone	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
	CCRT	0.599	1.0	0.599	0.682	0.432	0.988	0.471	0.569
	NAC+IMRT	0.463	0.064	0.476	0.228	0.067	0.990	0.113	0.924
	NAC+CCRT	0.297	0.595	0.414	0.448	0.982	0.028	0.082	0.492

Abbreviations: LRRFS, locoregional relapse-free survival; DMFS, distant metastases-free survival; PFS, progression-free survival; OS, overall survival; IMRT, intensity-modulated radiotherapy; CCRT, concurrent chemoradiotherapy; NAC, neoadjuvant chemotherapy. *The 7th AJCC/UICC staging system.