Table 3.
Variate | Category | p value | |||||||
---|---|---|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | ||||||||
LRRFS | DMFS | PFS | OS | LRRFS | DMFS | PFS | OS | ||
Age (years) | <50 | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
≥ 50 | 0.103 | 0.781 | 0.118 | 0.177 | 0.097 | 0.851 | 0.106 | 0.185 | |
Sex | Male | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
Female | 0.963 | 0.654 | 0.860 | 0.873 | 0.871 | 0.615 | 0.736 | 0.777 | |
T stage* | T1 | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
T2 | 0.093 | 0.665 | 0.095 | 0.319 | 0.121 | 0.742 | 0.114 | 0.317 | |
N stage* | N0 | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
N1 | 0.098 | 0.340 | 0.375 | 0.418 | 0.477 | 0.972 | 0.850 | 0.387 | |
Regimen | IMRT alone | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
CCRT | 0.599 | 1.0 | 0.599 | 0.682 | 0.432 | 0.988 | 0.471 | 0.569 | |
NAC+IMRT | 0.463 | 0.064 | 0.476 | 0.228 | 0.067 | 0.990 | 0.113 | 0.924 | |
NAC+CCRT | 0.297 | 0.595 | 0.414 | 0.448 | 0.982 | 0.028 | 0.082 | 0.492 |
Abbreviations: LRRFS, locoregional relapse-free survival; DMFS, distant metastases-free survival; PFS, progression-free survival; OS, overall survival; IMRT, intensity-modulated radiotherapy; CCRT, concurrent chemoradiotherapy; NAC, neoadjuvant chemotherapy. *The 7th AJCC/UICC staging system.