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. 2018 Jun 11;8:8848. doi: 10.1038/s41598-018-27252-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Short but not long reminder duration prevents memory recovery. Mean SCR (CS+ and CS−) during acquisition (late phase), extinction (late phase) and re-extinction (early phase) of the 5 experimental groups with different reminder durations. A significant 3-way interaction of group x stage x stimulus and follow-up t-tests confirmed memory recovery in the no-reminder, 30 s, and 3 min reminder groups, but not in the 1 s and 4 s reminder groups. **P < 0.01; ***P < 0.001. Error bars represent standard errors.