Fig. 1.

Claustrum receives dense innervation from anterior cingulate cortex (ACC) and projects to visual cortices (V1/V2) and parietal association cortex (PtA). a Left: photomicrograph showing anterograde neuronal tract tracer biotinylated dextran amine (BDA, 10,000 MW; green) injected into ACC. Right: BDA-labeled terminals (green) from ACC densely innervated contralateral claustrum at all three rostrocaudal levels of claustrum as depicted by the blue boxes in the anatomical cartoons above. b Left: photomicrograph showing retrograde tract tracer cholera toxin B subunit (CTb; red) injected into V1/V2. Right: CTb-labeled cells projecting to V1/V2 were found at all three rostrocaudal levels of ipsilateral claustrum. c Left: photomicrograph showing CTb (red) injected into PtA. Right: a dense population of CTb-labeled cells projecting to PtA were found at all three rostrocaudal levels of ipsilateral claustrum. STR striatum, CL claustrum, CTX cortex. Scale bars—200 µm