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. 2018 Jun 5;8:189. doi: 10.3389/fcimb.2018.00189

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Copyright © 2018 Chen, Elsheikha, Hu, Hu, Guo, Zhou and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histopathological changes in the liver tissues from Toxoplasma gondii-infected mice. Histopathological analysis was conducted on livers from mock- and T. gondii-infected mice at days 11 and 30 postinfection. Photomicrographs of liver tissue sections stained with hematoxylin and eosin (original magnification, × 100). (A) Liver section from a mouse on day 11 postinfection. Liver shows multifocal mononuclear cell aggregations (mainly lymphocytes, arrow) with numerous vacuolated hepatocyte. (B) At 30 dpi, liver shows mild mononuclear cellular infiltration (arrow), increased numbers of Von Kupffer cells besides numerous pyknotic hepatocytes. (C) Hepatic tissue from mock-infected, control mice shows a normal histological structure.