Skip to main content
. 2018 Jun 5;9:397. doi: 10.3389/fneur.2018.00397

Figure 4.

Figure 4

(A) Hemiplegia, i.e., disuse of the affected right forepaw, was evaluated in cylinder tests 7 days after surgery (i.e., postnatal day 19, P19). The number of forepaw contacts made with the wall during rearing were counted. Paw preference was calculated as follows: (left [non-impaired side]—right [impaired side])/(left + right) × 100%. (B) Sensorimotor skills were evaluated in rotarod tests 8 days after surgery (P20). The average time until the animal fell off the rotating drum in 5 consecutive sessions was analyzed. The box shown extends from the 25 to 75th percentiles. The whiskers shown are drawn down to the 5th and up to the 95th percentile. Points below and above the whiskers are drawn as individual dots. The no-surgery controls were combined with the sham group because there was no difference in performance between these groups. In the cylinder test, Wild Sham, n = 12; Wild HI-30 min, n = 16; Wild HI-50 min, n = 8; BMP-3b KO Sham, n = 22; BMP-3b KO HI-30 min, n = 12; and BMP-3b KO HI-50 min, n = 17. In the rotarod test, Wild Sham, n = 7; Wild HI-30 min, n = 10; Wild HI-50 min, n = 10; BMP-3b KO Sham, n = 25; BMP-3b KO HI-30 min, n = 12; and BMP-3b KO HI-50 min, n = 9. *p < 0.05.