Table 1.
Diagnostic test results.
| Date | Specimen | Microbiological test results | Pathological test results |
|---|---|---|---|
| 2006 | Bronchial washing right lower lobe | Culture negative for bacteria and fungi Auramine-rhodamine stain negative |
No arguments for malignancy |
| August 15, 2013 | Bronchial (brushing and) washing right lower lobe | Culture negative for bacteria and fungi Auramine-rhodamine stain negative |
Active inflammation No arguments for malignancy |
| September 03, 2013 | Computed tomography-guided biopsy right lower lobe | NA | Fibrosis with anthracosis and chronic inflammation No arguments for malignancy |
| September 23, 2013 | EBUS 10R | NA | Representative specimen of reactive lymph node without arguments for malignancy |
| October 29, 2013 | Wedge resection apical segment right lower lobe | Culture negative for bacteria | Fibrotic node with extensive chronic inflammation and bronchialization of the alveoli No arguments for malignancy No arguments for actinomyces infection |
| October 29, 2013 | Urine | Culture negative for bacteria and fungi | NA |
| November 04, 2013 | Blood | Culture negative for bacteria and fungi | NA |
| November 07, 2013 | Urine | Culture negative for bacteria and fungi | NA |
| November 07, 2013 | Wound fluid chest drain entrance | Sporadic S. aureus | NA |
| January 20, 2014 | Bronchial washing right lower lobe | Bacterial culture with commensal throat flora Culture negative for fungi Culture negative for actinomyces Culture negative for nocardia Auramine-rhodamine stain negative Culture negative for mycobacteria |
Active inflammation, sparse fungal hyphae and bacteria No arguments for malignancy |
| January 30, 2014 | Mediastinoscopy 4L and 7 | NA | Lymph node tissue without evidence of malignancy Extensive sinushistiocytosis at lymph node station 7 |
| March 31, 2014 | Cerebrospinal tap | NA | No arguments for malignancy or infection |
| May 02, 2014 | Skin biopsy | Bacterial culture with coagulase-negative staphylococci Fungal culture with Verticillium species and Aspergillus fumigatus |
Extensive active inflammation with a lobular panniculitis and localization of fungal hyphae No arguments for malignancy |
| May 02, 2014 | Wound fluid skin biopsy | Fungal culture with A. fumigatus | NA |
| May 13, 2014 | Serum | Galactomannan negative HIV 1 and HIV 2 antigen and immunoglobulin negative Toxoplasma gondii IgG positive, IgM negative Treponema pallidum immunoglobulin negative |
NA |
| May 13, 2014 | Blood (×2) | Culture negative for bacteria and fungi | NA |
| May 13, 2014 | Urine | Culture negative for bacteria and fungi | NA |
| May 19, 2014 | Serum | Cryptococcus neoformans antigen negative | NA |
| May 26, 2014 | Serum | Interferon-gamma release assay negative | NA |
| June 02, 2014 | Cerebral biopsy | Aspergillus fumigatus | Cerebral material with lytic cell remnants, active inflammation and presence of fungi (preference for Aspergillus) |
NA, not available.